About Liver Tumors
Neuroendocrine Liver Metastases
Neuroendocrine tumors are slow growing tumors
that are most often discovered when they have multiple metastatic deposits
within the liver, or outside the liver (extrahepatic), making them unresectable.
Because of hormone secretion, these patients experience higher death rates.
Even though few patients with metastatic neuroendocrine tumors are appropriate
for resection, significant symptom relief can be accomplished by treatments
intended to reduce, if not eliminate, the tumor. Treatment options include
hepatic artery ligation and chemoembolization to limit the sustaining blood
supply to the tumor(s) as well as local ablation techniques including radiofrequency
ablation, alcohol injection and cryotherapy.
However, in patients with resectable disease, resection may delay the most
debilitating symptoms for several years. A 1996 study reported five-year survival
rates of 79%, with 52% of these patients not experiencing any recurrence during
this period.