About Liver Tumors
Colorectal Cancer
Incidence
Colorectal (colon and rectum, or entire large bowel) cancer is the
fourth most common malignancy, behind cancers of the lung, breast and prostate.
Worldwide, colorectal cancer strikes approximately 850,000 people each
year and accounts for over 500,000 annual deaths. Up to 70% of patients with
colorectal cancer eventually develop liver metastases. In 30-40% of those patients
with metastases, it is still confined to the liver at the time of metastatic
diagnosis. Of the patients with colorectal metastases confined to the liver,
only 25% are surgical candidates due to size, distribution or accessibility
of the tumor(s).
Promising developments in minimally invasive intervention, however, do offer
local treatment options for patients with unresectable liver metastases confined
to the liver. This is the focus of this web site.
Prognosis
By definition, patients with metastatic disease have advanced stage
disease. Surgical resection is now a widely accepted treatment for colorectal
metastases to the liver. Five-year survival rates are consistently reported
between 20% and 35% for patients whose cancer is confined to the liver and
is surgically accessible. By contrast, patients with similar disease who
could not tolerate surgery, and did not receive any other treatment except
systemic chemotherapy, rarely survived for five years.